ResultsSearch results and characteristics of studiesElectronic and hand searches returned 7239 studies. The first stage selection excluded 6932 studies simply on the basis of language, year of publication, and reporting of relevant outcomes. The second stage selection screened 307 studies on the basis of methodological characteristics and included 23 of them in the final review.9 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 The web appendix lists these studies with their main characteristics and outcomes..
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